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Magnetic beads
Magnetic beads
Magnetic immunoassay (MIA) is a novel type of diagnostic immunoassay using magnetic beads as labels in lieu of conventional enzymes (ELISA), radioisotopes (RIA) or fluorescent moieties (fluorescent immunoassays). This assay involves the specific binding of an antibody to its antigen, where a magnetic label is conjugated to one element of the pair. The presence of magnetic beads is then detected by a magnetic reader (magnetometer) which measures the magnetic field change induced by the beads. The signal measured by the magnetometer is proportional to the analyte (virus, toxin, bacteria, cardiac marker,etc.) quantity in the initial sample.
Magnetic beads are made of nanometric-sized iron oxide particles encapsulated or glued together with polymers. These magnetic beads range from 35nm up to 4.5μm. The component magnetic nanoparticles range from 5 to 50nm and exhibit a unique quality referred to as superparamagnetism in the presence of an externally applied magnetic field. First discovered by Frenchman Louis Néel, Nobel Physics Prize winner in 1970, this superparamagnetic quality has already been used for medical application in Magnetic Resonance Imaging (MRI) and in biological separations, but not yet for labeling in commercial diagnostic applications. Magnetic labels exhibit several features very well adapted for such applications:
- they are not affected by reagent chemistry or photo-bleaching and are therefore stable over time,
- the magnetic background in a biomolecular sample is usually insignificant,
- sample turbidity or staining have no impact on magnetic properties,
- magnetic beads can be manipulated remotely by magnetism.
U0001-10 Magnetic bead carboxyl, 9.234Kč
U0001-20 Magnetic bead carboxyl, 15.002Kč
U0001-5 Magnetic bead carboxyl, 6.075Kč
U0002 Anti-HIS Magnetic Bead, 21.526Kč
U0003 Anti-GST Magnetic Bead, 17.749Kč
U0007-1 Protein A Magnetic Bead, 6.075Kč
U0007-5 Protein A Magnetic Bead, 17.749Kč
U0008 Protein G Magnetic Bead, 17.749Kč
U0009 Anti-human Fc Magnetic Bead, 17.749Kč
U0010 Anti-mouse Fc Magnetic Bead, 17.749Kč
U0011 Anti-mouse IgG Magnetic Bead, 17.749Kč
For information about precipitation system, which uses magnetic beads, please, visit this page.
Magnetic immunoassay (MIA) is a novel type of diagnostic immunoassay using magnetic beads as labels in lieu of conventional enzymes (ELISA), radioisotopes (RIA) or fluorescent moieties (fluorescent immunoassays). This assay involves the specific binding of an antibody to its antigen, where a magnetic label is conjugated to one element of the pair. The presence of magnetic beads is then detected by a magnetic reader (magnetometer) which measures the magnetic field change induced by the beads. The signal measured by the magnetometer is proportional to the analyte (virus, toxin, bacteria, cardiac marker,etc.) quantity in the initial sample.
Magnetic beads are made of nanometric-sized iron oxide particles encapsulated or glued together with polymers. These magnetic beads range from 35nm up to 4.5μm. The component magnetic nanoparticles range from 5 to 50nm and exhibit a unique quality referred to as superparamagnetism in the presence of an externally applied magnetic field. First discovered by Frenchman Louis Néel, Nobel Physics Prize winner in 1970, this superparamagnetic quality has already been used for medical application in Magnetic Resonance Imaging (MRI) and in biological separations, but not yet for labeling in commercial diagnostic applications. Magnetic labels exhibit several features very well adapted for such applications:
- they are not affected by reagent chemistry or photo-bleaching and are therefore stable over time,
- the magnetic background in a biomolecular sample is usually insignificant,
- sample turbidity or staining have no impact on magnetic properties,
- magnetic beads can be manipulated remotely by magnetism.
U0001-10 Magnetic bead carboxyl, 9.234Kč
U0001-20 Magnetic bead carboxyl, 15.002Kč
U0001-5 Magnetic bead carboxyl, 6.075Kč
U0002 Anti-HIS Magnetic Bead, 21.526Kč
U0003 Anti-GST Magnetic Bead, 17.749Kč
U0007-1 Protein A Magnetic Bead, 6.075Kč
U0007-5 Protein A Magnetic Bead, 17.749Kč
U0008 Protein G Magnetic Bead, 17.749Kč
U0009 Anti-human Fc Magnetic Bead, 17.749Kč
U0010 Anti-mouse Fc Magnetic Bead, 17.749Kč
U0011 Anti-mouse IgG Magnetic Bead, 17.749Kč
For information about precipitation system, which uses magnetic beads, please, visit this page.